Oxidative stress in Shaal sheep of different age groups

Authors: JAMILEH SALAR-AMOLI, ALI BAGHBANZADEH

Abstract: Oxidative stress plays an important role in the etiology and/or progression of a number of diseases and aging. In this cross-sectional study, some oxidative stress biomarkers (malondialdehyde [MDA] as a lipid peroxidation biomarker, ferric reducing/antioxidant power [FRAP], and total nonprotein SH groups) in plasma samples of Shaal ewes of different age groups were assessed. For all 3 measured parameters, the youngest age group (10-30 months old) had the lowest amounts. Although FRAP levels increased slightly and age dependently, nonprotein SH group content showed a decreasing trend after a peak in the 31-50 months group. The highest MDA concentration was observed in the oldest group. Our results suggest a relation between age and oxidative stress parameters in the early life of Shaal ewes. It also showed an age dependent increase in FRAP levels.

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