Single strand conformation polymorphism in intron I of the chicken apoVLDL-II gene, and its relationship with triglyceride and very low density lipoprotein concentrations

Authors: HASSAN HUSSEIN MUSA, GUO H. CHEN, JIN H. CHENG, WEN B. BAO, ADAM H. SULEIMAN

Abstract: Genetically fat and lean chickens reared identically in the same environment were used to investigate the effect of the apoVLDL-II gene (intron I) on total cholesterol, triglyceride, and lipoprotein concentrations. The overall allele frequency in the 2 populations was 0.59 for allele A and 0.41 for allele B. The allele frequency in the Rugao breed was 0.52 for allele A and 0.48 for allele B; however, in the Anka breed it was 0.65 for allele A and 0.35 for allele B. The apoVLDL-II genotype in the genetically fat Anka breed was associated with a significant increase in serum triacylglyceride concentration in sexually immature birds.

Keywords: PCR-SSCP, Apo VLDL-II, serum biochemical, chicken

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