Effect of Unilateral Adrenalectomy on the Blood Biochemistry of Black Bengal Goats (Capra hircus)

Authors: VEERASAMY SEJIAN, SAGAR SANYAL, PRADIP KR. DAS, PROBAL R. GHOSH, BALASUBRAMANIAN SIVAKUMAR, GURU D. V. PANDIYAN

Abstract: The present study was conducted to study the influence of unilateral adrenalectomy in the black Bengal goat and to observe its influence on stress alleviation capability in terms of changes in blood chemistry, and further emphasis was given to determine whether a single gland is sufficient for survival in these animals. Six female kids were unilaterally adrenalectomised and the other 6 were maintained as intact controls. Blood samples were drawn at regular intervals before and after surgery. Parameters included in the study were blood pH, blood volume, TEC, haemoglobin, PCV, TLC, differential leukocyte count, cortisol, glucose, total cholesterol, total protein, urea, and blood urea nitrogen. All the parameters were estimated by standard methods. All the blood biochemical parameters in the present study showed significant differences (P < 0.01) when compared to intact control animals. There was a significant increase in total plasma protein, total plasma cholesterol, blood urea, and blood urea nitrogen, and a significant decrease in plasma glucose and cortisol. The present study indicated that acute changes occurred in the blood biochemical parameters on unilateral adrenalectomy of the left adrenal gland that were later compensated for by the other intact right adrenal gland.

Keywords: Adrenalectomy, adrenal insufficiency, black Bengal goat, blood biochemistry, colorimetric method

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