Serum Biochemical Changes in Experimental Gambian Trypanosomosis. II. Assessing Hepatic and Renal Dysfunction

Authors: J. N. ABENGA, V. O. ANOSA

Abstract: Serum biochemical changes were assessed to determine hepatic and renal function in 4 vervet monkeys experimentally infected with Trypanosoma brucei gambiense, the causative agent of sleeping sickness in West and Central Africa. Parameters examined included serum bilirubin, blood urea nitrogen (BUN), and cholesterol levels. Significant increases in the total bilirubin and BUN levels occurred from the second week post-infection (PI) (P

Keywords: Serum biochemistry, trypanosomosis, human, monkeys

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