The Effects of Rumex patientia L. and Urtica dioica L. on Some Blood and Urine Parameters, and Liver and Kidney Histology in Diabetic Rats

Authors: HASAN V. GÜNEŞ, İRFAN DEĞİRMENCİ, MİRİŞ AYDIN, BERRİN BOZAN, ERİNÇ ARAL, ZEYNEP TUNALIER, CENGİZ ÜSTÜNER, MURAT ERÇAKAR, K. HÜSNÜ CAN BAŞER, AYŞE BAŞARAN

Abstract: The effects of Rumex patientia and Urtica dioica on levels of blood glucose, plasma amino acids and other parameters, urine excreta, and liver and kidney histology were examined in diabetic rats induced by streptozotocin. Streptozotocin increased blood glucose and changed the levels of amino acids and other parameters, and caused degenerative changes in the liver and kidney. Rumex patientia had some protective effect on these parameters changed by streptozotocin, while Urtica diocia had no protective effects.

Keywords: Amino acids; Creatinine clearance; HPLC; Rumex patientia; Streptozotocin; Enzyme; Urtica dioica

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