Seroprevalences and associated risk factors of hepatitis B and C in adults

Authors: MUSTAFA YILDIRIM, SELMA ÇAKIR, MEHMET FARUK GEYİK, DAVUT ÖZDEMİR, ERTUĞRUL GÜÇLÜ, MEHMET ÇAKIR

Abstract: Chronic hepatitis due to hepatitis B and hepatitis C virus infections is the most common cause of chronic liver disease. In this study we aimed to find out seroprevalences and associated risk factors of hepatitis B and C in adults in Düzce. Materials and methods: The sample of study was determined with a cluster-type sampling method. The study included 1321 people, consisting of 667 women and 654 men who were 18 years or older. A questionnaire about demographic information and risk factors was applied. Results: Seroprevalences of HBsAg, anti-HBs, and anti-HCV were 4.8%, 9.4%, and 0.7%, respectively. HBsAg seroprevalences were found to be statistically higher in the dental visit group (8.9% versus 4.0%, P = 0.002) and in people living within the same house with hepatitis B carriers (11.5% versus 4.6%, P = 0.036). Living in Düzce during the 1999 earthquake and staying in prefabricated houses after the earthquake were not risk factors of HBsAg carriage. Conclusion: HBsAg and anti-HCV seroprevalences in Düzce were in parallel with the previous data from Turkey and a low ratio of anti-HBs appeared. Identifying risk groups with large epidemiological screening studies and vaccination of nonimmune people are essential.

Keywords: Hepatitis B, hepatitis C, seroprevalence, risk factors, adults

Full Text: PDF