Compliance to treatment and reaching of metabolic goals are better in OAD-treated diabetics than insulin-treated diabetics in the Turkish population

Authors: SEMA UÇAK, EMİNE ŞATIR, OKCAN BASAT, YÜKSEL ALTUNTAŞ

Abstract: We assessed the success rates of reaching glycated haemoglobin (HbA1c) goals in different treatment groups. Materials and methods: This was a single-centre, retrospective study including 2995 patients. The proportion of patients reaching their HbA1c goals, according to the International Diabetes Federation (IDF), American Association of Clinical Endocrinologists (AACE), and American Diabetes Association (ADA), were determined. Results: There were 4 different treatment groups: 1) diet group (n = 140), 2) oral antidiabetic drug (OAD) group (n = 1238), 3) insulin group (n = 765), and 4) insulin + OAD group (n = 812). According to the IDF and AACE criteria, the proportion of patients reaching HbA1c levels of ≤6.5% was 92% in group 1, and 1 year later it was 100%. In the OAD group the proportions were 61% and 69%, respectively. In the insulin group, the rate was 15% and 1 year later 33% of patients had reached their goals. In the insulin + OAD group, the rates were 10% and 21%, respectively (P < 0.05 for all). According to the ADA criteria, the rate of patients reaching HbA1c levels of =<7% was 40% in the total group and, at the end of 1 year, 59%. In the diet group, the rates were 95% and 100%, respectively. In the OAD group, the rates were 75% and 83%, respectively. In the insulin group, the rates were 23% and 52%, respectively. In the insulin + OAD group, the rates were 16% and 32%, respectively. Conclusion: A large number of patients seemed to reach their HbA1c goals. The success rate was especially higher in the OAD group than in the insulin group.

Keywords: HbA1c goals, oral antidiabetic drugs, insulin

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