Endometrial parameters in IVF and IUI administration on elderly women

Authors: NAFİYE YILMAZ, SEVTAP KILIÇ, YUSUF MADENDAĞ, İLKNUR MADENDAĞ, AYLİN ÖZGÜN, GÜLNUR ÖZAKŞİT, SERTAÇ BATIOĞLU

Abstract: There are still controversial results about the role of endometrial thickness, pattern, volume, and vascularity in endometrial receptivity. We studied the predictivity of endometrial parameters in endometrial receptivity in over-aged, normogonadotrophic unexplained infertile women. Materials and methods: In this study, 150 women with an age range of 38-42 were included. The patients were divided into 4 groups: group 1 was applied recombinant FSH and intrauterine insemination, group 2 was applied clomiphene citrate and intrauterine insemination, group 3 was applied IVF, and group 4 (control group) was composed of fertile control patients. All patients in each study group had standard initiation dosages for ovulation induction. Endometrial thickness, volume, and colour Doppler results were evaluated according to their mean values. Results: The groups were homogeneous according to their age, body-mass-index, basal hormone levels, and maximum follicle diameter on the day of ovulation trigger injection. Endometrial thickness and pattern were significantly different between groups. The difference of endometrial volume was not statistically significant between groups. There were also no differences of uterine artery PI and RI between groups. The difference of spiral artery PI values between groups was statistically significant. When all groups are evaluated, effects of endometrial parameters on pregnancy were not different. Conclusion: Endometrial thickness, pattern, and volume, and RI and PI values for uterine and spiral arteries were found to have no predictive value on endometrial receptivity in over-aged, unexplained infertile women.

Keywords: IVF, IUI, endometrial thickness, endometrial volume, endometrial vascularity

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