Identification of Fibronectin Adhesins on Candida albicans

Authors: Gülhan VARDAR-ÜNLÜ

Abstract: The pattern of distribution of fibronectin adhesins on yeast and hyphal-form Candida albicanswas studied with gold-labelled fibronectin and transmission electron microscopy. The germ-tube parts of the hyphal-form cells were the major binding sites for gold-labelled fibronectin, and the attached yeast-cell parts and yeast-form cell remained unlabelled. Therefore, the walls of the germ tube parts of hyphal-form cells might be sites of important interactions between C. albicans and host tissues containing fibronectin.

Keywords: Candida abicans, adhesin, germ tube, fibronectin

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