The impact of NIH-IV prostatitis on early post-operative outcomes of The impact of NIH-IV prostatitis on early post-operative outcomes of transurethral resection of the prostate in patients with symptomatic benign prostate hyperplasia

Authors: FATİH RÜŞTÜ YALÇINKAYA, AHMET GÖKÇE, MÜRSEL DAVARCI, EŞREF OĞUZ GÜVEN, MEHMET İNCİ, SÜLEYMAN BARIŞ KARTAL, ALİ AYYILDIZ, MEVLANA DERYA BALBAY

Abstract: Transurethral prostate resection (TURP) is still considered the gold standard in the treatment of symptomatic benign prostate hyperplasia (BPH). Category IV chronic prostatitis (CP) is described by the National Institute of Health (NIH-IV) as the asymptomatic inflammation of the prostate and it may be detected along with benign prostate hyperplasia (BPH) during histological examinations of the prostate. In this study, we evaluate the impact of the presence of NIH-IV defined prostatitis on early post-operative outcomes of transurethral resection of the prostate. Materials and methods: Between 2004 and 2008, medical records of 247 patients who underwent TURP in Adana Numune Training and Research hospital were examined, retrospectively. Patients who had a histological diagnosis of only BPH were considered in Group 1 whereas Group 2 consisted of patients with both NIH-IV CP and BPH simultaneously. Factors such as total prostate specific antigen (tPSA) levels, International Prostate Symptom Scores (IPSS), single-question quality of life (QoL) assessments, maximum flow rates (Q max), residual urine volumes, catheterization times, re-catheterization rates, and the duration of re-catheterization were compared between these 2 groups. IPSS, QoL, and uroflowmetry measurements were compared between the 2 groups again at the third post-operative month. Statistical analysis with Student’s t and chi-square tests was performed with SPSS ® version 16. Results: Preoperatively, no statistically significant difference was present between the 2 groups with respect to IPSS, Q max, QoL, prostate volume, tPSA, and mean catheterization time (P > 0.05); however, re-catheterization rates were significantly different (P < 0.05). While meaningful difference was found between 90th day IPSS and QoL medians (P < 0.05), there was no difference in Q max medians (P > 0.05). Conclusion: NIH-IV chronic prostatitis shows negative effects on the subjective post-operative results and re-catheterization frequency of BPH patients that have undergone TURP.

Keywords: Chronic prostatitis, BPH, TURP, prostate, histology

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