Outcomes after lobectomy and pneumonectomy in lung cancer patients aged 70 years or older

Authors: İLKNUR AYTEKİN, MARUF ŞANLI, AHMET FERUDUN IŞIK, BÜLENT TUNÇÖZGÜR, AHMET ULUŞAN, KEMAL BAKIR, SEVAL KUL, LEVENT ELBEYLİ

Abstract: Background/aim: For the early stage of nonsmall-cell lung cancer, surgical resection provides the best survival, but the surgical risk generally increases with age because of the increased prevalence of comorbidities, especially cardiovascular disorders. The aim of this study was to compare survival and mortality rates of two groups with different ages, younger and older than 70 years, who went curative resection for nonsmall-cell lung cancer. Materials and methods: We analyzed the patients who underwent curative lung cancer surgery in the Department of Thoracic Surgery of Gaziantep University Research Hospital between January 1997 and November 2014. Patients were divided into 2 groups according to their ages. Results: A total of 497 patients were included in data analysis (381 were under 70 years old and 116 of them were ≥70 years old). The older group showed a 1.4-fold increased risk of mortality hazard ratio when the probability of survival was analyzed by histological type, lymph node involvement, disease stage, and age. Conclusion: There was no distinct increase in 30-day mortality rates of patients with nonsmall-cell lung cancer who were ≥70 years old, but the hazard rate for long-term survival was higher in the older group. Curative pulmonary resections due to lung cancer should be carefully performed in septuagenarians.

Keywords: Nonsmall-cell lung cancer, survival rate, elderly

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