Acute Effects of Extracorporeal Shock Wave Lithotripsy on Hepatic and Pancre

Authors: Özkan POLAT, Osman GÜL, Ahmet A. BALIK, Yılmaz AKSOY, Hikmet ELMAS, Yılmaz BAYRAKTAR

Abstract: Extracorporeal shock wave lithotripsy (ESWL), which is the most reliable, and noninvasive treatment for urolithiasis, can cause serious side effects, through of tissue damage. We researched the relationship between ESWL and hepatic and pancreatic enzymes, as well as the relationship between localization of stones and those enzymes, in 110 patients who had undergone ESWL. There were significant elevations in alkaline phosphatase (ALP), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), alanine aminotransferase (ALT), total and direct bilirubin, amylase and lipase levels after ESWL, but these elevations were below the maximal normal borders. AST and ALT showed greater elevation in the presence of right renal stones, and amylase in the presence of left renal stones. The other enzyme elevations had wo courelation with localization of the stones. ESWL is still the most reliable treatment for urolithiasis in view of the fact that these side effect are clinically insignificant and reversible.

Keywords: ESWL, hepatic enzymes, pancreatic enzymes