A Rare Side Effect of Metformin: Metformin-Induced Hepatotoxicity

Authors: ERSİN AKSAY, SEDAT YANTURALI, BAŞAK BAYRAM, NİL HOCAOĞLU, SELAHATTİN KIYAN

Abstract: Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this drug, metformin-induced hepatotoxicity has been rarely reported in the literature. We present herein the case of a 52-year-old male in whom metformin-associated lactic acidosis and metformin-induced hepatotoxicity developed.

Keywords: Metformin, metformin-associated lactic acidosis, hepatotoxicity, side effect

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