Treatment of ankylosing spondylitis

Authors: İSMAİL SARI, MEHMET AKİF ÖZTÜRK, NURULLAH AKKOÇ

Abstract: Abstract: Ankylosing spondylitis is a chronic, inflammatory, rheumatic disease that can reduce the quality of life and increase the risk of disability and mortality. It also causes direct and indirect economic losses due to health expenses and as a result of workforce loss. Management of this disease consists of pharmacological and nonpharmacological modalities. Until recently, pharmacological treatment options have been very limited. However, development of novel biological drugs revolutionized the management of this disease. The aim of this review article is to present an updated overview of the pharmacologic treatment of ankylosing spondylitis. Nonpharmacological treatment modalities including physiotherapy and exercise are only briefly mentioned and surgical treatment is not discussed.

Keywords: Ankylosing spondylitis, treatment, nonsteroid antiinflammatory drugs, disease modifying antirheumatic drugs, corticosteroids, anti-TNF agents

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