The effects of thyroid hormones on uroflowmetry parameters in asymptomatic women

Authors: ERSİN ÇİMENTEPE, MEHMET EROL YILDIRIM, İLKAY BEKİR İNCEBAY, AYŞE ÇARLIOĞLU, ÖMER FARUK KARATAŞ, DOĞAN ÜNAL

Abstract: To investigate whether there is any association between uroflowmetry parameters and blood levels of thyroid hormones in asymptomatic women. Materials and methods: Included in the study were 110 consecutive female patients with no urinary complaints who had thyroid function tests performed in an endocrinology clinic. Uroflowmetric measurements were performed for each patient in a sitting position. The patients were divided into 3 groups, hypo-, hyper-, and euthyroidism, and were investigated for statistical difference among them regarding maximum flow rate (Qmax), average flow rate (Qave), voided volume (VV), and voiding time (VT). Results: The mean Qmax and Qave values of hypo-, eu-, and hyperthyroid groups were 25.3 ± 9.1 and 14.9 ± 5.8, 28.6 ± 9.6 and 16.2 ± 6.4, and 21.5 ± 8.7, and 13.2 ± 5.6, respectively. In the evaluation of all groups, a statistically significant difference was found regarding Qmax (P = 0.004) and Qave (P = 0.024). When the groups were evaluated between each other, Qmax (p = 0.003) and Qave (P = 0.027) were significantly different between hyper- and euthyroid groups, with no statistically significant differences in other groups regarding the uroflowmetry parameters (P > 0.05). Conclusion: It has been found that Qmax and Qave were significantly lower in the hyperthyroid group as compared with the euthyroid group. According to these findings, it may be thought that hyperthyroidism negatively affects uroflowmetry parameters. To reach a definitive judgment, more investigations supported by urodynamic studies are necessary.

Keywords: uroflowmetry, thyroid hormone, urination

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