Cyanoacetamide Derivatives as Synthons in Heterocyclic Synthesis

Authors: AHMED ALI FADDA, SAMIR BONDOCK, RAMY RABIE, HASSAN ALI ETMAN

Abstract: This review presents a systematic and comprehensive survey of the methods of preparation and the chemical reactivity of cyanoacetamide derivatives. These compounds are important intermediates for the synthesis of a variety of otherwise difficult to obtain synthetically useful and novel heterocyclic systems.

Keywords: Cyanoacetanilide, thiophene, pyrazole, thiazole, pyridine, pyridazine, pyrimidine, heterocycles

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