Basic Al_2O_3 as a Recyclable Reagent for the Protection of Carbonyl Groups with Phenylhydrazine Derivatives and Semicarbazides

Authors: KHODABAKHSH NIKNAM, ALI REZA KIASAT, BAHADOR KARAMI, NIMA HEYDARI

Abstract: Basic alumina is employed as an inorganic basic solid catalyst for the clean and less hazardous protection of carbonyl compounds, such as phenylhydrazones, 2,4-dinitrophenylhydrazones, semicarbazones, and thiosemicarbazones, under solvent-free conditions. The reactions proceed smoothly and require a short reaction time with good to excellent yields, and the alumina used can be recycled.

Keywords: Basic alumina, phenylhydrazine derivatives, semicarbazides, carbonyl compounds, protection, recyclable

Full Text: PDF