Synthesis, Spectroscopic (FT-IR, ^1H, ^{13}C, Mass Spectrometry), and Biological Investigation of Five-Coordinated Germanium-Substituted Tricyclohexyl Antimony Dipropionates: Crystal Structure of Tricyclohexylantimony Dibromide

Authors: MUHAMMAD KALEEM KHOSA, MUHAMMAD MAZHAR, SAQIB ALI, KIERAN C. MOLLOY, SARIM DASTGIR, FARKHANDA SHAHEEN

Abstract: A series of five-coordinated germanium-substituted tricyclohexylantimony dipropionates have been synthesized and characterized by different instrumental techniques, such as elemental analyses, FT-IR, multinuclear NMR (^1H, ^{13}C) and mass spectrometry. These compounds have also been screened against different microbes and they showed good activity against different bacteria that was comparable to the reference drugs. The crystal structure of the precursor (C_6H_{11})_3SbBr_2 is reported here, which showed that the antimony atom in an asymmetric unit exists in trigonal bipyramidal geometry, having space group C2/c with the monoclinic crystal system.

Keywords: Organoantimony, organogermanium, spectroscopy, biological studies

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