Efficient Synthesis of 1-Alkoxycarbonyl-Methyl-2-Alkylpyrroles from Dichloro- and Methoxychloropropylalkyl Ketones

Authors: RAIK A. GADZHILI, RAYA A. NADZHAFOVA, ÖZGE ŞEŞENOĞLU

Abstract: The condensation reaction of 2,3-dichloropropyl- and 2-methoxy-3-chloropropyl alkyl ketones with alkyl 2-aminoacetate salts leads to 1-alkoxy-carbonylmethyl-2-alkylpyrroles. These compounds, with various bases, gave 1-carbamoylmethyl-, 1-dialkylaminocarbonylmethyl-, 1-carbazoyl methyl-2-alkylpyrroles and potassium salt of 2-alkyl-pyrrolyl-1-acetic acid.

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