Three-component synthesis of cyclic $\beta $-aminoesters using CeO$_{2}$ nanoparticles as an efficient and reusable catalyst

Authors: JAVAD SAFAEI GHOMI, SIMA KALHOR, HOSSEIN SHAHBAZI-ALAVI, Mehrnoosh ASGARI-KHEIRABADI

Abstract: CeO$_{2}$ nanoparticles were used as an efficient catalyst for the preparation of cyclic $\beta $-aminoesters by three-component reaction between primary amines, ethyl acetoacetate, and chalcones in ethanol. Atom economy, low catalyst loading, reusable catalyst, and high yields of products are some of the important features of this protocol.

Keywords: Cyclic $\beta $-aminoesters, reusable catalyst, CeO$_{2}$ nanoparticles, chalcones, one-pot

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