Synthesis of \alpha-aminonitriles catalyzed by montmorillonite K10 in the presence of dicationic phosphonium salt in water under ultrasonic effect

Authors: ÇİĞDEM YILDIRIM, ÇİĞDEM YOLAÇAN, FERAY AYDOĞAN

Abstract: The synthesis of \alpha-aminonitriles was successfully accomplished by the 1-pot 3-component reaction of several aldehydes with (S)-\alpha-phenylethylamine and sodium cyanide in water in the presence of montmorillonite K10 and dicationic phosphonium salt under ultrasonic effect with good yields and moderate diastereoselectivities.

Keywords: \alpha-Aminonitrile, Strecker synthesis, montmorillonite K10, dicationic phosphonium salt

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