H_2{SO}_4-silica as an efficient and chemoselective catalyst for the synthesis of acylal from aldehydes under solvent-free conditions

Authors: SEIED ALI POURMOUSAVI, ZAHRA ZINATI

Abstract: A variety of aldehydes react with acetic anhydride in the presence of a catalytic amount of H_2SO_4-silica to afford the corresponding 1,1-diacetates (acylals) in excellent yields. Ketones are not affected under the reaction conditions. The advantages are the simplicity of the acylation procedure, and the relatively non-toxic nature of the catalyst as well as its easy availability and low cost.

Keywords: Acylals, aldehydes, catalysis, solvent-free reactions, H_2SO_4-silica.

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