6-O-\alpha-L-Rhamnopyranosylcatalpol Derivative Iridoids from Verbascum cilicicum

Authors: İ. İREM TATLI, ZELİHA Ş. AKDEMİR, ERDAL BEDİR, IKHLAS A. KHAN

Abstract: From the aerial parts of Verbascum cilicicum Boiss., 6 iridoid glycosides, namely catalpol (1), verbaspinoside [= 6-O-(2'' -O-trans-cinnamoyl)-\alpha-L-rhamnopyranosylcatalpol] (2), 6-O-(3''-O-trans-cinna\-moyl)-\alpha-L-rhamnopyranosylcatalpol (3), 6-O-(4''-O-trans-cinnamoyl)-\alpha -L-rhamnopyranosylcatalpol (4), saccatoside [= 6-O-(2''-O-trans-p-coumaroyl)-\alpha-L-rhamnopyranosylcatalpol] (5), and 6-O-(3''-O-trans-p-coumaroyl)-\alpha-L-rhamnopyranosylcatalpol (6), were isolated. The structures of the compounds were elucidated by means of 1 and 2 dimensional (DQF-COSY, HMQC and HMBC) NMR techniques and LC-ESIMS.

Keywords: Verbascum cilicicum, Scrophulariaceae, iridoid glycosides, catalpol (1), verbaspinoside (2), 6-O-(3'' -O-trans-cinnamoyl)-\alpha-L-rhamnopyranosylcatalpol (3), 6-O-(4''-O-trans-cinnamoyl)-\alpha-L-rham\-nopyranosylcatalpol (4), saccatoside (5), 6-O-(3''-O-trans-p-coumaroyl)-\alpha-L-rhamnopyranosylcatalpol (6)

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