Phenolic, Megastigmane, Nucleotide, Acetophenon and Monoterpene Glycosides from Phlomis samia and P. carica

Authors: FUNDA NURAY YALÇIN, TAYFUN ERSÖZ, PINAR AKBAY, İHSAN ÇALIŞ, ALİ ARSLAN DÖNMEZ, OTTO STICHER

Abstract: Phytochemical investigations on the aerial parts of Phlomis samia resulted in the isolation of a simple phenolic glucoside, 2,6-dimethoxy-4-hydroxyphenol-1-O-\beta -D-glucopyranoside (1); a megastigmane glucoside, phlomuroside (=3-hydroxy-5,6-epoxy-\beta -ionol-9-O-\beta -D-glucopyranoside) (2); and a nucleotide glycoside, uridine (3). From the aerial parts of P. carica, the same phenolic glucoside, 2,6-dimethoxy-4-hydroxyphenol-1-O-\beta -D-glucopyranoside (1); as well as an acetophenon glucoside, picein (4); and 2 monoterpenoid glucosides, - betulalbuside A (5) and 1-hydroxylinaloyl-6-O-\beta -D-glucopyranoside (6) - were isolated and identified. The structure elucidation of the isolates was based on spectroscopic evidence.

Keywords: Acetophenon glucoside, betulalbuside A, 2,6-dimethoxy-4-hydroxy- phenol-1-O-\beta -D-glucopyranoside, 1-hydroxylinaloyl-6-O-\beta -D-glucopyranoside, Lamiaceae, megastigmane glucoside, mono\-terpenoid glucosides, nucleotide glycoside, Phlomis samia, P. carica}, phenolic glucoside, phlomuroside, picein, uridine

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