Chemical Constituents of Centaurea cuneifolia

Authors: ÜMİT ASLAN, SEVİL ÖKSÜZ

Abstract: The whole plant material fo Centaurea cuneifolia Sm. afforded three sesquiterpene lactones; cnicin (1), dehydromelitensin (2) and dehydromelitensin-8-[(2^{'}-\alpha-hydroxy-\beta- hydroxyethyl)-acryloyl)] (3), the lignan; (-)-arctigenin (4), flavonoids; salvigenin (5), eupatilin (6), jaceosidin (7), acacetin (8), kaemferol (9), 5,7,4^{'}-trihydroxy-3-methylether (10), 5-hydroxy-3^{'},^{'},6,7-tetramethoxyflavone (11) and 5-hydroxy-3^{'},4^{'},7,8-tetramet hoxyflavone (12), a triterpene; \alpha-amyrin and a sterol; \beta-sitosterol. The structures of the isolates were determined by IR, UV, ^1H and ^{13}C NMR and MS spectroscopy.

Keywords: Centaurea cuneifolia; Compositae; sesquiterpene lactones; elemanolide; lignan; flavonoids; triterpenes; steroids.

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