Synthesis and Reactivity of Some Mannich Bases. VI. New Arylamine Mannich Bases Derived From 2-Hydroxy-5-Methylacetophenone

Authors: GHEORGHE ROMAN, DIANA NANU, EUGENIA COMANITA, BOGDAN COMANITA

Abstract: The amine exchange reaction has been applied for obtaining a new series of arylamine Mannich bases from variously substituted aromatic amines and 3-(dimethylamino)-1-(2'-hydroxy-5'-methylphenyl) propan-1-one. The structures of the newly synthesised Mannich bases have been investigated by IR, ^1H- and ^{13}C-NMR and shown to be in good agreement with the proposed ones.

Keywords: Mannich bases, amine-exchange reaction, arylamines, \beta-arylaminoketones, ortho-hydroxyacetophenones

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