The Synthesis of 2-(Chloromethyl)-6-Hydroxy-2H-Pyran-3 (6H)-one via Achmatowicz Rearrangement

Authors: ZUHAL GERÇEK

Abstract: Achmatowicz rearrangement was carried out with 2-chloro-1-(furan-2-yl) ethanol, which was synthesized starting from 1-(furan-2-yl) ethanone. It was shown that the oxidation of 2-chloro-1-(furan-2-yl) ethanol with m-CPBA produced 2-(chloromethyl)-6-hydroxy-2H-pyran-3 (6H)-one in good yield (70%).

Keywords: Oxidation, furan, 2-chloro-1-(furan-2-yl) ethanol, m-CPBA, rearrangement, pyranones

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