Lewis Acid Catalyzed 1,3-Dipolar Cycloadditon Reactions of Stabilized Azomethine Ylides

Authors: ÖZDEMİR DOĞAN, HASAN KOYUNCU, ÜMİT KANIŞKAN

Abstract: Diethylzinc was tested for the first time as the Lewis acid in 1,3-dipolar cycloaddition reactions of azomethine ylides to synthesize pyrrolidine derivatives. A new, easily applicable and highly selective method was developed for the synthesis of highly substituted pyrrolidines. By the application of this method, the synthesis of three new pyrrolidine derivatives was achieved.

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