Synthesis and Antifungal Properties of Some Benzimidazole Derivatives

Authors: GÜLGÜN AYHAN KILCIGİL, NURTEN ALTANLAR

Abstract: Some benzimidazole derivatives were synthesized and their in vitro antifungal activities were tested against Candida albicans, Candida glabrata and Candida krusei. Compounds 6 and 9 possessed activity comparable to fluconazole against C. albicans with a minimum inhibitory concentration of 12.5 \mu g/mL.

Keywords: Benzimidazole, thiourea, antifungal

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