Facile and convenient synthesis of pyrimidine, 4H-3,1-benzoxazin-4-one, pyrazolo[5,1-b]quinazoline, pyrido[1,2-a]quinazoline, and chromeno[3' ,4' :4,5]pyrido[1,2-a]quinazoline derivatives

Authors: YOUSRY A. AMMAR, SAMIR BONDOCK, ABDALLAH G. EL-SEHMI, MOHAMED S.A EL_GABY, AHMED M. FOUDA, HAMDY KH. THABET

Abstract: A convenient synthesis of a series of pyrimidine, 4H-3,1-benzoxazin-4-one, pyrazolo[5,1-b]quinazoline, pyrido[1,2-a]quinazoline, and chromeno[3' ,4' :4,5]pyrido[1,2-a]quinazoline derivatives, via the reactions of versatile and readily accessible methyl 2-(2-cyanoacetamido)benzoate (1) with the appropriate reagents, is described here.

Keywords: Cyanoacetanilide, pyrimidine, quinazoline, pyrazolo[5,1-b]quinazoline, pyrido[1,2-a]quinazoline

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