Synthesis of new N-[3-(Benzo[d]thiazol-2-yl)-4-methylthiazol-2(3H)-ylidene] substituted benzamides

Authors: AAMER SAEED, HUMMERA RAFIQUE

Abstract: A series of novel N-[3-(2-benzo[d]thiazol-2-yl)-4-methylthiazol-2(3H)-ylidene] substituted benzamides (2a--k) were efficiently synthesized by heterocyclization of the corresponding 1-(benzo[d]thiazol-2-yl)-3-aroylthioureas (1a--k). The cyclization was achieved by the reaction of \alpha-bromoacteone produced in situ using bromine in dry acetone in the presence of triethylamine.

Keywords: N-[3-(2-Benzothiazolyl)-4-methylthiazol-2(3H)-ylidene] substituted benzamides, 1-(benzo[d] thiazol-2-yl)-3-aroylthioureas, 2-aminobenzothiazoles

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