Binding of permanganate anion to pentaammineazidocobalt(III) cation in solution and solid phases: synthesis, characterization, X-ray structure, and genotoxic effects of [Co(NH₃)₅N₃](MnO₄)₂•H₂O

Authors: RITU BALA, JINKWON KIM, VINIT PRAKASH

Abstract: A pentaammineazidocobalt(III) complex, [Co(NH₃)₅N₃](MnO₄)₂XH₂O has been synthesized by an one-pot synthesis method. It was characterized by studies such as infrared (IR) and UV-visible spectroscopy. The single crystal X-ray structure analysis revealed that the title complex crystallizes in space group Cc. The cobalt center is six coordinated with slightly octahedral geometry. The supramolecular architecture is also formed by intermolecular N-H…O (anion and H₂O) and Mn-O…O-H hydrogen bonds. The binding property of the cation, [Co(NH₃)₅N₃]²⁺ with the anion, MnO₄^- has also been determined (in solution phase) with the help of UV-visible spectroscopic titrations. Further, the genotoxic effects of KMnO₄, [Co(NH₃)₅N₃]Cl₂ and [Co(NH₃)₅N₃](MnO₄)₂XH₂O were studied using Allium cepa root chromosomal aberration assay and it revealed that the genotoxicity of the newly synthesized complex is 1.97-1.76 fold, which is less compared to KMnO₄ . The order of genotoxic potential has been observed to be KMnO₄ > [Co(NH₃)₅N₃](MnO₄)₂XH₂O > [Co(NH₃)₅N₃]Cl₂.

Keywords: Anion binder, pentaammineazidocobalt(III), coordination chemistry, genotoxicity, IR spectroscopy, X-ray crystallography

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