Isolation and Structure Elucidation of Novel Natural Products from Turkish Lichens

Authors: SÜHEYLA KIRMIZIGÜL, ÖMER KOZ, HÜSEYİN ANIL, SIDDIK İÇLİ, ULVİ ZEYBEK

Abstract: Three natural products were isolated from three different Turkish lichens. Microbiological investigations were also examined of these lichens. Compound 1 is known as 2-hydroxy-4-methoxy-3,6-dimethyl benzoic acid, and is isolated from Pseudevernia furfuracea for the first time. Compounds 2 and 3 are detected as new compounds and called, 3-acetyl-4-amino-2-chloro-1- (4-hydroxy-2-methoxy- 6-methylphenyl carbonyloxy) benzene and 2-(4-methoxyphenyl)-2-(5-oxo-4-phenyl-2,5- dihydro-2-furaniliden) acetic acid; they were isolated from Evernia prunastri and Letharia vulpina, respectively. All these compounds had different skeletons. Their structures were established by chemical methods and spectroscopic techniques using IR, UV, 1D and 2D NMR and EI and (+) FAB-Mass methods.

Keywords: Turkish lichens, Pseudevernia furfuracea, Evernia prunastri, Letharia vulpina, Phenolic compounds.

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