Novel N-acyl/aroyl-2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazides: synthesis and characterization

Authors: AAMER SAEED, MAJID HUSSAIN, MUHAMMAD QASIM

Abstract: A number of novel N-acyl/aroyl-2-(5-phenyl-2H-tetrazol-2-yl)acetohydrazides (4a--j) of biological interest were efficiently synthesized by treating 2-(5-phenyl-2H-tetrazole-2-yl)acetohydrazide (3) with a variety of aroyl/hetero- cyclyl or alkanoyl chlorides. FTIR, ^1H NMR, ^{13}C NMR, GC-MS, and elemental analyses data confirmed the structures assigned to the newly synthesized compounds.

Keywords: Tetrazoles, hydrazides, acylation

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