Synthesis and Some Reactions of 4-Benzoyl-5-Phenyl-1-Pyridin-2-yl-1H- Pyrazole-3-Carboxylic Acid

Authors: AHMET ŞENER, ESVET AKBAŞ, M. KASIM ŞENER

Abstract: The 1H-pyrazole-3-carboxylic acid 2, obtained from the furandione 1 and 2-hydrazinopyridine, was decarboxylated to give 4-benzoyl-5-phenyl-1-pyridin-2-yl-pyrazole derivative 3. Some ester 4 derivatives of 2 were prepared by the Fischer esterification reactions of 2 with various alcohols. Cyclocondensation reactions of 2 with phenyl hydrazine or hydrazine hydrate led to the formation of derivatives of pyrazolo[3,4-d]pyridazine 5 derivatives.

Keywords: Cyclic oxalyl compounds, Pyrazole, Pyrazolo [3,4-d] Pyridazinone

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