Iridoid and Phenylpropanoid Glycosides from Phlomis grandiflora var. fimbrilligera and Phlomis fruticosa

Authors: TAYFUN ERSÖZ, İCLAL SARACOĞLU, Ü. ŞEBNEM HARPUT, İHSAN ÇALIŞ, ALİ ARSLAN DÖNMEZ

Abstract: From the aerial parts of Phlomis grandiflora var. fimbrilligera, two iridoid glucosides, 8-epi-loganin (1) and auroside (2), together with five phenylethanoid glycosides, forsythoside B (3), alyssonoside (4), verbascoside (5), hattushoside (6) and phlomisethanoside (7), were isolated. Iridoid glucosides auroside (2) and lamiide (8) and phenylethanoid glycosides, forsythoside B (3), alyssonoside (4), and verbascoside (5) as well as a lignan glucoside, syringaresinol-4 ' -O-\beta -D-glucoside (9), were characterized from the overground parts of P. fruticosa. The structures of the isolates were elucidated by means of one and two dimensional (COSY, HSQC and HMBC) NMR techniques and ESI MS.

Keywords: Phlomis grandiflora, Phlomis fruticosa, Lamiaceae, iridoid glucosides, phenylethanoid glycosides, lignan glucoside.

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