Antioxidant, anticholinesterase, and antimicrobial activities and fatty acid constituents of Achillea cappadocica Hausskn. et Bornm.

Authors: ABDULSELAM ERTAŞ, MEHMET BOĞA, NESRİN HAŞİMİ, YETER YEŞİL, AHMET CEYHAN GÖREN, GÜLAÇTI TOPÇU, UFUK KOLAK

Abstract: This study was the first fatty acid analysis and biological activity report on an endemic Achillea species, Achillea cappadocica Hausskn. et Bornm. The major compounds in the fatty acid were identified as oleic (34.7 %), palmitic (23.1 %), and linoleic acids (20.6 %). The methanol and water extracts indicated higher ABTS cation radical scavenging activity than that of \alpha-tocopherol and BHT at 100 \mu g/mL. The acetone extract showed 70.62 % inhibitory activity against butyrylcholinesterase at 200 \mu g/mL. The acetone and methanol extracts exhibited moderate antimicrobial activity.

Keywords: Asteraceae, Achillea cappadocica, fatty acid, antioxidant, nticholinesterase, antimicrobial

Full Text: PDF