Mesoporous silica nanoparticles SBA-15 loaded with emodin upregulate the antioxidative defense of Euproctis chrysorrhoea (L.) larvae

Authors: MILENA JANKOVIC-TOMANIC, DAJANA TODOROVIC, ZORAN STANIVUKOVIC, VESNA PERIC MATARUGA, LUDGER WESSJOHANN, GORAN KALUDJEROVIC

Abstract: The study presented here aims to elucidate the effects of emodin (EO = 1,3,8-trihydroxy-6-methylanthraquinone) in its free form and when loaded into a mesoporous silica nanocarrier SBA-15 (→ SBA-15|EO) on the activities of the main antioxidative enzymes, superoxide dismutase, catalase, glutathione S-transferase, and glutathione reductase, in larvae of a polyphagous insect pest, the browntail moth Euproctis chrysorrhoea (L.). The results show that only SBA-15|EO upregulates the activities of the tested antioxidative enzymes. These results point to significant differences in the effectiveness of the compound in the free versus the loaded form.

Keywords: Euproctis chrysorrhoea, emodin, mesoporous nanosilica carrier SBA-15, antioxidative enzymes

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